2nd MIPS – Makassar, Indonesia

di Presentasikan pada acara 2nd Makassar Internasional Pharmaseutical Science Symposium, 20 – 22 Maret 2013

THE EFFECT OF EXTRACTION METHOD OF Eleutherine americana Merr. IN DECREASING OF BLOOD GLUCOSE LEVELS ACTIVITY ON MICE (Mus musculus)

Islamudin Ahmad, Yurika Sastyarina
Faculty of Pharmacy, Mulawarman University
East Kalimantan, Indonesia Tel/Fax. : (0541) 73949 E-mail: islamudinahmad@yahoo.com

ABSTRACT

The aim of this study was to know the pharmacological effect of Red bulb plant commonly known as “bawang dayak” (Eleutherine Americana Merr.) on mice which would be focused on the effect in decreasing blood glucose level from three different methods extractions an maceration, reflux and soxhlet using methanol solvent. Besides that, it has been done determining for TLC profile and which gives the best separation in eluen n-hexane : ethyl acetat with comparison 2:1 and eluent chloroform: methanol with comparison 5:1. According to the result of blood glucose decreasing and organ index change consist of the significantly different among three extraction methods (p<0,05).

Keywords: Eleutherine Americana Merr., Extraction methods, TLC, Blood Glucose

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