ISLAMUDIN AHMAD

Indian Journal of Pharmaceutical Sciences. Volume 79, Issue 6

Extraction of Polyphenolic Content from Peperomia pellucida (L) Kunth Herb with 1-Ethyl-3-methylimidazolium Bromide as Green Extraction

*Corresponding Author:
I. Ahmad
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
E-mail: islamudinahmad@farmasi.unmul.ac.id
Date of Submission 11 November 2016
Date of Revision 26 March 2017
Date of Acceptance 25 September 2017
Indian J Pharm Sci 2017;79(6): 1013-1017

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Abstract

Extraction of the polyphenolic content from Peperomia pellucida (L) Kunth herb (Piperaceae family) using 1-ethyl-3-methylimidazolium bromide as a solvent was attempted. The herbs were extracted using the ionic liquid-based microwave-assisted extraction method with some combination factors such as extraction time, microwave power, liquid-solid ratio, and ionic liquid concentration. The optimum yields of total polyphenolic content (13.750 µg GAE/g sample) were obtained by using a microwave power of 30 % Watt, extraction time of 10 minutes, the liquid-solid ratio of 14 ml/g, and ionic liquid concentration of 0.7 mol/l. Based on the results, compared to conventional organic solvent, the solvent of 1-ethyl-3-methylimidazolium bromide could provide higher extraction yields of polyphenolic content. Moreover, the extraction of a secondary metabolite from this herb becomes more rapid, easy, and efficient.

Keywords

Peperomia pellucida (L). Kunth, 1-ethyl-3-methylimidazolium bromide, ionic liquid, microwave assisted extraction, total polyphenolic content

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