Indian Journal of Pharmaceutical Sciences. Volume 79, Issue 6

Extraction of Polyphenolic Content from Peperomia pellucida (L) Kunth Herb with 1-Ethyl-3-methylimidazolium Bromide as Green Extraction

*Corresponding Author:
I. Ahmad
Department of Pharmaceutical Sciences, Faculty of Pharmacy, Universitas Indonesia, Depok, Indonesia
Date of Submission 11 November 2016
Date of Revision 26 March 2017
Date of Acceptance 25 September 2017
Indian J Pharm Sci 2017;79(6): 1013-1017

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms


Extraction of the polyphenolic content from Peperomia pellucida (L) Kunth herb (Piperaceae family) using 1-ethyl-3-methylimidazolium bromide as a solvent was attempted. The herbs were extracted using the ionic liquid-based microwave-assisted extraction method with some combination factors such as extraction time, microwave power, liquid-solid ratio, and ionic liquid concentration. The optimum yields of total polyphenolic content (13.750 µg GAE/g sample) were obtained by using a microwave power of 30 % Watt, extraction time of 10 minutes, the liquid-solid ratio of 14 ml/g, and ionic liquid concentration of 0.7 mol/l. Based on the results, compared to conventional organic solvent, the solvent of 1-ethyl-3-methylimidazolium bromide could provide higher extraction yields of polyphenolic content. Moreover, the extraction of a secondary metabolite from this herb becomes more rapid, easy, and efficient.


Peperomia pellucida (L). Kunth, 1-ethyl-3-methylimidazolium bromide, ionic liquid, microwave assisted extraction, total polyphenolic content

Link Download: Click Here

Be Sociable, Share!

Be the first to comment

Leave a Reply

Your email address will not be published.